Cunard ship Queen Elizabeth will operate the new sailings
The Queen Elizabeth, the first in the fleet to return to service with UK sailings in the summer, will visit 32 ports in 12 countries.
The cruises will run between 20 February and 21 June, 2022.
Destinations from Southampton include the Norwegian fjords; Spain and Portugal; the Mediterranean; and transiting the Panama Canal to Alaska.
The programme includes six overnight port calls and three late evening departures.
Extended time in Tromso and Narvik in Norway offers the possibility of seeing the Northern Lights
A call in Amsterdam on a four-night short break brings an opportunity to explore the city by night.
Other highlight calls include Genoa, Ibiza, Manzanillo, Grand Turk, San Francisco and Alaska’s Glacier Bay National Park and Hubbard Glacier.
Outgoing Cunard president Simon Palethorpe said: “We’re thrilled to offer this exciting new Escapes Programme to guests who might long for a voyage that promises a sense of freedom, luxury and style.
“For cruise afficionados or those enjoying their first taste of the vibrant and inviting world of Queen Elizabeth, together with our renowned white star service, this programme has something for everyone.”